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Index > Protein center > Rorb(Gene name) > Rat
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  • Rorb (Gene name),
  • Nuclear receptor ROR-beta (Protein name ),  RORB_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Rorb(Nr1f2;Rzrb);
    Protein name:
    Nuclear receptor ROR-beta;
    Alternative:
    Nuclear receptor subfamily 1 group F member 2;Nuclear receptor RZR-beta;Retinoid-related orphan receptor-beta;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Orphan nuclear receptor required for normal postnatal development of rod and cone photoreceptor cells. Regulates transcription of OPN1SW in cone photoreceptor cells by binding the sequence 5'-AGGTCA-3' in the OPN1SW promoter.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    470
    Sequence:
    50:
    MCENQLKTKA | DGTAQIEVIP | CKICGDKSSG | IHYGVITCEG | CKGFFRRSQQ | 
    100:
    NNASYSCPRQ | RNCLIDRTNR | NRCQHCRLQK | CLALGMSRDA | VKFGRMSKKQ | 
    150:
    RDSLYAEVQK | HQQRLQEQRQ | QQSGEAEALA | RVYSSSISNG | LSNLNTETGG | 
    200:
    TYANGHVIDL | PKSEGYYNID | SGQPSPDQSG | LDMTGIKQIK | QEPIYDLTSV | 
    250:
    HNLFTYSSFN | NGQLAPGITM | SEIDRIAQNI | IKSHLETCQY | TMEELHQLAW | 
    300:
    QTHTYEEIKA | YQSKSREALW | QQCAIQITHA | IQYVVEFAKR | ITGFMELCQN | 
    350:
    DQILLLKSGC | LEVVLVRMCR | AFNPLNNTVL | FEGKYGGMQM | FKALGSDDLV | 
    400:
    NEAFDFAKNL | CSLQLTEEEI | ALFSSAVLIS | PDRAWLLEPR | KVQKLQEKIY | 
    450:
    FALQHVIQKN | HLDDETLAKL | IAKIPTITAV | CNLHGEKLQV | FKQSHPDIVN | 
    470:
    TLFPPLYKEL | FNPDCAAVCK | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Nuclear receptor ROR-beta
    Cat.:
    E10639h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Nuclear receptor ROR-beta
    Cat.:
    E10639m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat Nuclear receptor ROR-beta
    Cat.:
    E10639r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Nuclear receptor ROR-beta
    Cat.:
    U10639h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Nuclear receptor ROR-beta
    Cat.:
    U10639r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Nuclear receptor ROR-beta
    Cat.:
    U10639m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Rat Nuclear receptor ROR-beta
    Cat.:
    P10639Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Nuclear receptor ROR-beta
    Cat.:
    P10639Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Nuclear receptor ROR-beta
    Cat.:
    P10639Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Nuclear receptor ROR-beta
    Monoclonal Antibody for Rat Nuclear receptor ROR-beta
    Monoclonal Antibody for Rat Nuclear receptor ROR-beta
    Protein for Rat Nuclear receptor ROR-beta
    Protein for Rat Nuclear receptor ROR-beta
    Protein for Rat Nuclear receptor ROR-beta

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "RZRs, a new family of retinoid-related orphan receptors that function as both monomers and homodimers."
      Carlberg C. , Hooft van Huijsduijnen R. , Staple J.K. , Delamarter J.F. , Becker-Andre M.
      Mol. Endocrinol.8:757-770(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
      strain: Sprague-Dawley.
      tissue: Brain.
    2. 2.
      "A novel isoform of the orphan nuclear receptor RORbeta is specifically expressed in pineal gland and retina."
      Andre E. , Gawlas K. , Becker-Andre M.
      Gene216:277-283(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION AS TRANSCRIPTION ACTIVATOR (ISOFORMS 1 AND 2);TISSUE SPECIFICITY;DNA-BINDING;INDUCTION
    3. 3.
      "Functional analysis of retinoid Z receptor beta, a brain-specific nuclear orphan receptor."
      Greiner E.F. , Kirfel J. , Greschik H. , Doerflinger U. , Becker P. , Mercep A. , Schuele R.
      Proc. Natl. Acad. Sci. U.S.A.93:10105-10110(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS TRANSCRIPTION MODULATOR;SUBUNIT;DNA-BINDING;DOMAIN
    4. 4.
      "Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice."
      Andre E. , Conquet F. , Steinmayr M. , Stratton S.C. , Porciatti V. , Becker-Andre M.
      EMBO J.17:3867-3877(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation."
      Stehlin C. , Wurtz J.-M. , Steinmetz A. , Greiner E. , Schuele R. , Moras D. , Renaud J.-P.
      EMBO J.20:5822-5831(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 212-463 IN COMPLEX WITH STEARIC ACID AND NCOA1 PEPTIDE;DOMAIN;MUTAGENESIS OF ALA-280; TYR-457 AND GLU-459
    6. 6.
      "All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta."
      Stehlin-Gaon C. , Willmann D. , Zeyer D. , Sanglier S. , van Dorsselaer A. , Renaud J.-P. , Moras D. , Schule R.
      Nat. Struct. Biol.10:820-825(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.5 ANGSTROMS) OF 219-462 IN COMPLEX WITH RETINOIC ACID AND PEPTIDE SRC-1;FUNCTION AS TRANSCRIPTION ACTIVATOR;IDENTIFICATION OF LIGANDS
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